Ionic liquids (ILs) have received considerable attention in the separation science community due to their unique physical and chemical properties. Several excellent review articles on the application of ILs in analytical chemistry have been published. Rather than provide another comprehensive overview, this review focuses on the development and state-of-the-art of ILs in capillary electrophoresis (CE) for enantioseparation. The contents are divided into six sections according to the application modes of ILs, including achiral ILs modified conventional chiral separation system, chiral ILs synergistic separation system, chiral ILs ligand-exchange CE (LE-CE) system, ILs in micellar electrokinetic chromatography (MEKC), the development of novel ILs chiral selectors, and some other applications. The critical research questions and solutions of each application modes are systematically summarized. Existing problems and future prospects are also discussed.

离子液体（ILs）由于其独特的物理和化学特性而在分离科学界引起了相当大的关注。关于IL在分析化学中的应用的几篇优秀评论文章已经发表。本综述没有提供其他全面的概述，而是着重于毛细管电泳（CE）中对映体分离中IL的发展和最新技术。根据离子液体的应用方式，将内容分为六个部分，包括非手性离子液体改良的常规手性分离系统，手性离子液体协同分离系统，手性离子液体配体交换CE（LE-CE）系统，胶束电动色谱法（MEKC）中的离子液体。 ），新型ILs手性选择剂的开发以及其他一些应用。系统总结了每种应用模式的关键研究问题和解决方案。还讨论了现有问题和未来前景。