AbstractNitrogen doped carbon dots (NCDs) were synthesized using a low temperature approach and used to modify a glassy carbon electrode (GCE) via dipping. The oxygen groups on the surface of the NCDs, and the charge delocalization of the NCDs warrant an excellent electrocatalytic activity of the GCE toward oxidation of paracetamol (PA) and reduction of H2O2. PA and H2O2 were detected at 0.34 V and −0.4 V (both vs. Ag/AgCl) using differential pulse voltammetry and amperometric I-T measurement, respectively. The modified GCE has a linear response to PA in the 0.5 to 600 μM concentration range, and to H2O2 in the 0.05 μM to 2.25 mM concentration range. The detection limits are 157 nM and 41 nM, respectively. In our perception, the modified GCE holds promise for stable, selective and sensitive determination of PA and H2O2 in pharmaceutical analysis. Graphic abstractNitrogen doped carbon dots (NCDs) were synthesized and used to modify a glassy carbon electrode. Surface functional groups on NCDs can trigger electrocatalytic reactions toward paracetamol oxidation and H2O2 reduction with high sensitivities.

中文翻译：

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一种用 N 掺杂碳点修饰的玻碳电极，用于改进过氧化氢和扑热息痛的检测

摘要 采用低温法合成了氮掺杂碳点 (NCDs)，并通过浸渍法对玻碳电极 (GCE) 进行改性。NCDs 表面的氧基团和 NCDs 的电荷离域保证了 GCE 对扑热息痛 (PA) 的氧化和 H2O2 的还原具有出色的电催化活性。PA 和 H2O2 分别使用差分脉冲伏安法和电流型 IT 测量在 0.34 V 和 -0.4 V（均与 Ag/AgCl 相比）下检测到。修改后的 GCE 对 0.5 至 600 μM 浓度范围内的 PA 和 0.05 μM 至 2.25 mM 浓度范围内的 H2O2 具有线性响应。检测限分别为 157 nM 和 41 nM。在我们看来，改进的 GCE 有望在药物分析中稳定、选择性和灵敏地测定 PA 和 H2O2。图形摘要氮掺杂碳点 (NCD) 被合成并用于修饰玻碳电极。NCDs 上的表面官能团可以以高灵敏度触发对乙酰氨基酚氧化和 H2O2 还原的电催化反应。