A gold-catalyzed method for the construction of indolizines with eight-membered rings has been developed. The reaction proceeded through a two-fold hydroarylation with indole or pyrrole derivatives containing a 1,6-diyne using a tri(1-adamantyl)phosphine gold complex as the catalyst, affording 1,8-disubstituted indolizines in moderate to good yields in DCE at 80 °C. The potential usefulness of these indolizines as blue or green OLEDs has been also disclosed.

中文翻译：

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通过金催化的二炔二元氢芳基化反应合成含八元环的吲哚嗪衍生物

已经开发了一种金催化的八元环吲哚嗪的构建方法。该反应通过使用三（1-金刚烷基）膦金络合物作为催化剂，与含有1,6-二炔的吲哚或吡咯衍生物进行两次氢化芳基化反应，在DCE中得到中等至良好收率的1,8-二取代的吲哚并嗪在80°C下。还已经公开了这些吲哚嗪作为蓝色或绿色OLED的潜在用途。