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Modification of microfluidic paper-based devices with dye nanomaterials obtained by encapsulation of compounds in Y and ZSM5 zeolites
Sensors and Actuators B: Chemical ( IF 8.4 ) Pub Date : 2018-01-06 , DOI: 10.1016/j.snb.2018.01.071
Ana Raquel Bertão , Nuno Pires , António M. Fonseca , Olívia S.G.P. Soares , Manuel F.R. Pereira , Tao Dong , Isabel C. Neves

Zeolite nanostructures were used as hosts for dyes normally used in some bioassays (pH and protein), and applied on microfluidic paper-based analytical devices (μPADs). The obtained dye nanomaterials were characterized by several techniques (structural (FTIR and XRD), surface (SEM/EDX), textural (N2 adsorption) analyses and dye loading determination by TGA analysis), to confirm the stability of both host and guest. After their deposition on the paper’s surface, the color change was studied by analyzing the RGB values, taking into account the lifetime and the results stability of the μPADs. These results confirmed that both the lifetime and the color change of the modified devices were stable over one week. It was also demonstrated that the choice of the paper for the μPAD as well as the zeolite nanostructures properties influences the colorimetric response. This strategy by encapsulating dyes into zeolites solve current challenges in colorimetric sensors in where long-term stability of the colorimetric results is an issue. The results obtained were promising for the studied assays, and the strategy could also be extended to other bioassays.



中文翻译:

用染料纳米材料修饰微流体纸基器件,该染料纳米材料是通过将化合物封装在Y和ZSM5沸石中而获得的

沸石纳米结构被用作通常在某些生物测定中使用的染料(pH和蛋白质)的主体,并应用于基于微流体纸的分析设​​备(μPAD)。通过几种技术(结构(FTIR和XRD),表面(SEM / EDX),质构(N 2))对获得的染料纳米材料进行了表征。吸附)分析和通过TGA分析确定染料负载量,以确认宿主和客体的稳定性。将它们沉积在纸张表面后,通过分析RGB值来研究颜色变化,同时考虑了μPAD的寿命和结果稳定性。这些结果证实,改性器件的寿命和颜色变化在一个星期内都是稳定的。还证明了对μPAD纸的选择以及沸石纳米结构的性质都会影响比色响应。通过将染料封装到沸石中的这种策略解决了比色传感器中的当前挑战,在该挑战中,比色结果的长期稳定性是一个问题。获得的结果对于所研究的测定是有希望的,并且该策略也可以扩展到其他生物测定。

更新日期:2018-01-06
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