当前位置: X-MOL 学术Clin. Infect. Dis. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Urine Tuberculosis Lipoarabinomannan Predicts Mortality in Hospitalized Human Immunodeficiency Virus-Infected Children
Clinical Infectious Diseases ( IF 11.8 ) Pub Date : 2018-01-06 , DOI: 10.1093/cid/ciy011
Sylvia M LaCourse 1 , Lisa M Cranmer 2, 3 , Irene N Njuguna 4, 5 , John Gatimu 6 , Joshua Stern 7 , Elizabeth Maleche-Obimbo 6 , Judd L Walson 1, 4, 7, 8, 9 , Dalton Wamalwa 6 , Grace C John-Stewart 1, 4, 7, 8 , Patricia B Pavlinac 7
Affiliation  

Despite diagnostic performance limitations, urine lipoarabinomannan (LAM) predicts death in human immunodeficiency virus (HIV)–infected adults with tuberculosis. Pediatric data are limited. Among 137 hospitalized HIV-infected children, mortality was 4.9-fold higher among those with positive LAM (127 vs 31 per 100 person-years; adjusted hazard ratio, 4.92; 95% confidence interval [CI], 1.79–13.49; P = .002). Lipoarabinomannan identifies HIV-infected children at risk for death potentially missed by respiratory sampling.

中文翻译:

尿结核Lipoarabinomannan预测住院的人类免疫缺陷病毒感染儿童的死亡率。

尽管诊断性能受到限制,但尿脂阿拉伯糖甘露聚糖(LAM)仍可预测感染了人类免疫缺陷病毒(HIV)的成年人的死亡。儿科数据有限。在137名接受HIV感染的住院儿童中,LAM阳性的儿童的死亡率高4.9倍(每100人年127比31;调整后的危险比为4.92; 95%置信区间[CI]为1.79–13.49;P =。 002)。Lipoarabinomannan识别出呼吸道采样可能遗漏的有HIV感染危险的儿童死亡。
更新日期:2018-01-06
down
wechat
bug