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Pd-Catalyzed Remote Meta-C–H Functionalization of Phenylacetic Acids Using a Pyridine Template
Organic Letters ( IF 5.2 ) Pub Date : 2018-01-05 00:00:00 , DOI: 10.1021/acs.orglett.7b03336
Zhong Jin 1 , Ling Chu 1 , Yan-Qiao Chen 1 , Jin-Quan Yu 1
Affiliation  

An effective pyridine based U-shaped template has been developed to enable a diverse range of meta-C–H functionalizations of phenylacetic acid scaffolds. This new template has extended the reaction scope to cross-coupling with ArBF3K as well as iodination using 1,3-diiodo-5,5-dimethylhydantoin as the iodination reagent.

中文翻译:

Pd催化使用吡啶模板的苯乙酸的远程Meta -CH功能

已开发出一种有效的基于吡啶的U形模板,可实现苯乙酸支架的多种间位-C–H官能化。该新模板将反应范围扩展到与ArBF 3 K交叉偶联以及使用1,3-二碘-5,5-二甲基乙内酰脲作为碘化试剂的碘化反应。
更新日期:2018-01-05
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