Postsynthetic treatments are well-known and important functionalization tools of metal–organic frameworks (MOFs). Herein, we have developed a practical and rapid postsynthetic ligand exchange (PSE) strategy using a defect-controlled MOF. An increase in the number of defects amounts to MOFs with enhanced rates of ligand exchange in a shorter time frame. An almost quantitative exchange was achieved by using the most defective MOFs. This PSE strategy is a straightforward method to introduce a functionality into MOFs including bulky or catalytically relevant moieties. Furthermore, some mechanistic insights into PSE were revealed, allowing for a sequential ligand exchange and the development of multifunctional MOFs with controlled ligand ratios.

中文翻译：

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缺陷工程到金属有机框架中，以快速顺序地安装功能

合成后处理是金属有机框架（MOF）的众所周知且重要的功能化工具。在这里，我们已经开发了使用缺陷控制的MOF的实用和快速的合成后配体交换（PSE）策略。缺陷数量的增加等于MOF在更短的时间内具有更高的配体交换率。通过使用最有缺陷的MOF，可以实现几乎定量的交换。此PSE策略是将功能引入MOF（包括庞大或催化相关部分）的直接方法。此外，揭示了对PSE的一些机械见解，从而可以进行顺序的配体交换并开发出具有受控配体比率的多功能MOF。