Alkylation of the [nido-5,6-R¹₂C₂B₈H₉]⁻ anions (where R¹ = H and Me) with alkyl halides (RX, where R = primary and secondary alkyls) in boiling tetrahydrofuran (THF) proceeds via unusual H₂ elimination, followed by cage closure to give a series of the neutral closo-1,2-R¹₂C₂B₈H₇-3-R derivatives in ∼70–80% yields. In contrast, treatment of the unsubstituted [nido-5,6-C₂B₈H₁₁]⁻ anion with tert-butyl bromide (t-BuBr) led to the formation of the parent closo-1,2-C₂B₈H₁₀ in >85% yield. The constitution of all compounds isolated has been confirmed unambiguously by multinuclear (¹¹B, ¹H, and ¹³C) nuclear magnetic resonance measurements and α-shift correlation assessments.

中文翻译：

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的3烷基衍生物特异合成：通过烷基化的十顶点尼多笼的不寻常的封闭closo- 1,2--C ₂乙₈ ħ ₁₀

[ nido -5,6 -R ¹ ₂ C ₂ B ₈ H ₉ ] ^-阴离子（其中R ¹ = H和Me）与烷基卤化物（RX，其中R =伯和仲烷基）在沸腾的四氢呋喃（THF）中进行烷基化）通过异常的H ₂消除过程进行，然后关闭笼子，以约70-80％的产率得到一系列中性closo -1,2-R ¹ ₂ C ₂ B ₈ H ₇ -3-R衍生物。相反，未取代的[ nido -5,6 -C ₂ B ₈ H ₁₁ ]的处理⁻与叔丁基溴化物（t -BuBr）形成阴离子，以> 85％的收率形成母体closo -1,2-C ₂ B ₈ H ₁₀。通过多核（¹¹ B，¹ H和¹³ C）核磁共振测量和α位移相关性评估已明确确认了所有分离出的化合物的组成。