An absorbance enhanced probe based on gold nanoparticles (GNPs) was proposed for a protein assay in the cerebrospinal fluid of a rat brain. The GNPs, assembled with two aptamers by proximity ligation, have high anti-salt properties, and good selectivity and response toward proteins, such as interferon-gamma, in the brain.

中文翻译：

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适体/ GNP的吸光度增强可在大鼠大脑中检测灵敏的蛋白质

提出了一种基于金纳米颗粒（GNPs）的吸光度增强探针，用于大鼠脑脊髓液中的蛋白质测定。通过邻近连接与两个适体组装的GNP具有高抗盐特性，并且对大脑中的蛋白质（例如干扰素-γ）具有良好的选择性和响应性。