Electronic cigarettes enabling enhanced airflow have grown in popularity in recent years. The objective of this study is to show that flow rates modulate the levels of specific aerosol toxicants produced in electronic cigarettes. Flow rates used in various laboratory investigations involving e-cigarettes have varied widely to date, and can thus promote interlaboratory variability in aerosol product profiles. The thermal decomposition of hydroxyacetone and glycolaldehyde is less favorable at lower temperatures, supporting the observations of these products at higher flow rates/lower heating coil temperatures. Higher temperatures promote the formation of acetaldehyde from hydroxyacetone and formaldehyde from both hydroxyacetone and glycolaldehyde. A separate finding is that greater airflow can also expose users to concerning levels of e-liquid solvents. Under the modest conditions studied, propylene glycol aerosol levels are found at above the acceptable inhalation levels defined by NASA, and in range of the generally recognized as safe levels for daily ingestion.

中文翻译：

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电子烟气流速率会调节有毒物质的分布并可能导致溶剂消耗量达到令人担忧的水平

近年来，能够增强气流的电子烟越来越受欢迎。本研究的目的是表明流速调节电子烟中产生的特定气溶胶毒物的水平。迄今为止，涉及电子烟的各种实验室研究中使用的流量差异很大，因此可以促进气雾剂产品特性的实验室间差异。羟基丙酮和乙醇醛的热分解在较低温度下不太有利，这支持了这些产品在较高流速/较低加热盘管温度下的观察结果。较高的温度促进羟基丙酮形成乙醛以及羟基丙酮和乙醇醛形成甲醛。另一项发现是，更大的气流也会使用户接触到一定程度的电子烟液溶剂。在研究的适度条件下，发现丙二醇气溶胶水平高于 NASA 定义的可接受吸入水平，并且在普遍认为的日常摄入安全水平范围内。