We developed novel caffeine-imprinted conducting polymer sensors with 2D hierarchical pore arrays. Colloidal mask-assisted electrochemical polymerization was used to design the molecularly imprinted conducting polymers (MICPs). First, 2D MICP micropore arrays were obtained by electropolymerization on 2D polystyrene (PS) colloidal arrays (d = 1 μm) fabricated via colloidal lithography. As a second step, each of two smaller PS colloids (d = 200 and 500 nm) was aligned onto the MICP pores, and second step electropolymerization was performed to fabricate hierarchical pore arrays. Relative to the single MICP pore array (MICP1) film, the two designed MICP films (MICP1-200 and MICP1-500) showed highly enhanced sensing properties such as sensing capacity, sensitivity, and selectivity. MICP1-200 film with nanoscale porous MICP network formed in each micropore exhibited significantly improved sensing behaviors, superior to MICP1-500 film. This sensing improvement is attributed to well-controlled MICP pore structures increasing the recognition cavities during surface imprinting. Thus, this novel strategy can be extensively used for the development of various MICP-based sensors.

我们开发了具有2D分层孔阵列的新型咖啡因印迹导电聚合物传感器。胶体掩模辅助的电化学聚合被用来设计分子印迹的导电聚合物（MICPs）。首先，通过在 通过胶体光刻技术制造的2D聚苯乙烯（PS）胶体阵列（d = 1μm）上进行电聚合，获得2D MICP微孔阵列。第二步，将两个较小的PS胶体（d  = 200和500 nm）分别对准MICP孔，然后进行第二步电聚合以制造分层的孔阵列。相对于单个MICP孔阵列（MICP1）膜，设计的两种MICP膜（MICP1-200和MICP1-500）显示出高度增强的感测特性，例如感测能力，灵敏度和选择性。在每个微孔中形成具有纳米级多孔MICP网络的MICP1-200膜，其传感行为显着改善，优于MICP1-500膜。这种感测的改善归因于良好控制的MICP孔结构，增加了表面压印过程中的识别腔。因此，这种新颖的策略可以广泛用于各种基于MICP的传感器的开发。