In 2001, the INTERGENE research programme established a population-based cohort of 3614 adults living in south-western Sweden. The aim was to assess environmental, lifestyle and hereditary risk factors for cardio-metabolic and respiratory diseases, and to document secular changes in many of these characteristics. Because the focus is on coronary heart disease (CHD), the population cohort was complemented with 618 patients with acute or chronic CHD who were sampled during the examination period for the cohort (2001–04), following the same protocol. More than 800 variables describe lifestyle and socio-demographic characteristics from questionnaires, anthropometric characteristics from physical examinations, and biomarkers from blood sampled during the examination. Additional blood samples and extracted DNA are stored in biobanks. Data from the case-control study of CHD were used to investigate associations between common risk factors (overweight,...

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同类研究：INTERGENE研究

2001年，INTERGENE研究计划在瑞典西南部建立了一个以人口为基础的3614名成年人的队列。目的是评估心脏，代谢和呼吸系统疾病的环境，生活方式和遗传风险因素，并记录许多这些特征的长期变化。因为重点放在冠心病（CHD）上，所以该人群队列补充了618例急性或慢性CHD患者，这些患者在该队列的检查期间（2001-04年）按照相同的方案进行了采样。超过800个变量描述了调查表中的生活方式和社会人口统计学特征，体格检查中的人体测量学特征以及检查期间采样的血液中的生物标志物。额外的血液样本和提取的DNA被存储在生物库中。