The Melbourne Collaborative Cohort Study (MCCS), also known as Health 2020, was planned in the late 1980s and established in the early 1990s as an omnibus cohort to investigate prospectively the roles of diet and lifestyle in causing cancer and other non-communicable diseases.¹ It was developed contemporaneously with the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort² at a time when diet and nutrition were considered important to cancer causation,³ but detailed information adequate to inform prevention was scant. The literature was dominated by inconsistent evidence generated by a large number of small case-control studies which had problems not only with statistical power and dietary assessment but also, more importantly, with forms of information bias to which such studies are prone. A prospective design was chosen to...

中文翻译：

---

队列简介：墨尔本协作队列研究（2020年健康状况）

墨尔本协作队列研究（MCCS），也称为“健康2020”，计划于1980年代末建立，并于1990年代初建立，作为一项综合队列研究，对饮食和生活方式在引起癌症和其他非传染性疾病中的作用进行前瞻性研究。¹这是欧洲前瞻性研究癌症和营养（EPIC）队列同时开发²在这个时候饮食和营养被认为是癌症的因果关系，重要的³但是缺乏足够的信息来预防。大量小型病例对照研究产生的不一致证据主导了文献，这些研究不仅在统计能力和饮食评估方面存在问题，而且更重要的是，这类研究容易出现信息偏倚的形式。选择了前瞻性设计来...