2007 was a year of renewed possibilities in stem cell research. iPSCs had just been discovered, genome-wide sequencing technologies were coming online, and the ISSCR was expanding its international influence and membership. It was also the year that Cell Stem Cell published its first papers. Over a decade later, we again find ourselves eagerly anticipating the next stage in the development of the field with application of stem cell-based therapies moving closer to clinical reality, and the study of embryos and pluripotent stem cells yielding unprecedented insights into human development and disease. This period also marks a kind of lineage transition for the journal as our founding Editor, Deborah Sweet, moves on to a broader role at Cell Press. It’s my honor and privilege to take over as Editor in Chief of Cell Stem Cell at this exciting time in stem cell research. I’m grateful to be building on the efforts of such a dedicated and thoughtful leader. Debbie launched this journal as a labor of love, and she instilled a deep sense of responsibility to the community, fairness in our editorial practices, and an enthusiasm for stem cell science into the lifeblood of the journal. Coming from the same lineage, I am committed to bringing that same ethos forward under my guidance.

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