In this issue of Cell Stem Cell, Yui et al. (2018) show how tissue regeneration is driven by changes in the microenvironment. During intestinal regeneration, the epithelium is reprogrammed into a fetal state by an altered extracellular matrix (ECM), which is dependent on YAP/TAZ activation.

中文翻译：

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考虑环境：通过细胞外基质进行细胞重编程。

在本期的《细胞干细胞》中，Yui等人。（2018）显示了微环境变化如何驱动组织再生。在肠道再生过程中，上皮细胞通过改变的细胞外基质（ECM）重新编程为胎儿状态，这取决于YAP / TAZ激活。