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Non-natural amino acid peptide microarrays to discover Ebola virus glycoprotein ligands
Chemical Communications ( IF 6.319 ) Pub Date : 2018-01-03 , DOI: 10.1039/C7CC08242H
Joshua A. Rabinowitz, John C. Lainson, Stephen Albert Johnston, Chris W. Diehnelt

We demonstrate a platform to screen a virus pseudotyped with Ebola virus glycoprotein (GP) against a library of peptides that contain non-natural amino acids to develop GP affinity ligands. This system could be used for rapid development of peptide-based antivirals for other emerging or neglected tropical infectious diseases.
更新日期:2018-01-03

 

Some contents have been Reproduced with permission of the American Chemical Society.
Some contents have been Reproduced by permission of The Royal Society of Chemistry.
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