We demonstrate a platform to screen a virus pseudotyped with Ebola virus glycoprotein (GP) against a library of peptides that contain non-natural amino acids to develop GP affinity ligands. This system could be used for rapid development of peptide-based antivirals for other emerging or neglected tropical infectious diseases.

中文翻译：

---

非天然氨基酸肽微阵列发现埃博拉病毒糖蛋白配体

我们展示了一个平台，可针对包含非天然氨基酸以开发GP亲和配体的肽库筛选以埃博拉病毒糖蛋白（GP）假型化的病毒。该系统可用于快速开发基于肽的抗病毒药，以治疗其他正在出现或被忽视的热带传染病。