A mild method for synthesizing carboxylic acids by oxidation of aldoximes using hypervalent iodine reagents†,Organic & Biomolecular Chemistry

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A mild method for synthesizing carboxylic acids by oxidation of aldoximes using hypervalent iodine reagents†
Organic & Biomolecular Chemistry ( IF 3.2 ) Pub Date : 2018-01-02 00:00:00 , DOI: 10.1039/c7ob02858j
Akira Nakamura _{1,

2,

3,

4} , Hodaka Kanou _{1,

2,

3,

4} , Junki Tanaka _{1,

2,

3,

4} , Akira Imamiya _{1,

2,

3,

4} , Tomohiro Maegawa _{1,

2,

3,

4} , Yasuyoshi Miki _{1,

2,

3,

4,

5}

Affiliation

A mild oxidation method for the conversion of aldoximes to carboxylic acids was developed mediated by hypervalent iodine reagents. This method covers a wide range of functionalized aldoximes and proceeds under mild conditions, utilizing PhI(OH)OTs as an oxidant.

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