The aim of the study was to evaluate the spatial variations in the biomechanical properties of the bone around the implants retrieved from human subjects due to fixture head fracture after almost 20 years of loading. The implant-in-bone specimens were prepared for the histomorphometry and nanoindentation test to measure the bone-to-implant contact ratio (BIC ratio) and elastic modulus (E) of peri-implant bone. The indentations were performed in the up, center, down, and away regions of the bone tissues within all the thread spaces. The BIC ratios were 91.0% for Patient #1 and 95.8% for Patient #2. The E values assessed from the up region within the thread spaces were significantly higher than those measured from the center region. The elastic properties assessed from center and down regions within the thread spaces were similar to those assessed from the away region. The representative E values showed no significant thread-dependent linear trend. Within the limitation of this study, the peri-implant bone tissue showed spatial variation of its elastic modulus after long-term functioning.

这项研究的目的是评估在受力近20年后，由于固定器头部骨折而从人类受试者取回的植入物周围骨骼的生物力学特性的空间变化。准备骨植入物标本用于组织形态计量学和纳米压痕测试，以测量植入物周围骨的骨与植入物接触比（BIC比）和弹性模量（E）。压痕在所有螺纹空间内的骨组织的上，中，下和远离区域进行。患者＃1的BIC比率为91.0％，患者＃2的BIC比率为95.8％。从螺纹空间内的向上区域评估的E值显着高于从中心区域测量的E值。从螺纹空间内的中心和下部区域评估的弹性性质与从远离区域评估的弹性性质相似。代表性的E值没有显示出明显的与螺纹相关的线性趋势。在这项研究的限制内，植入物周围的骨组织在长期运行后显示出其弹性模量的空间变化。