α‐Aminoalkylation of N‐arylacrylamides with amino acid derivatives was achieved by silver‐catalysis in moderate to high yields. The reaction provides an efficient strategy for the synthesis of functionalized oxindoles, and is suitable for a wide range of N‐arylacrylamides and amino acids, both of which are inexpensive and readily available. The oxindoles obtained were readily transformed into densely functionalized pyrroloindolines by deprotection and cyclization in one pot.

中文翻译：

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银催化N-芳基丙烯酰胺与氨基酸衍生物的α-氨基烷基化反应，高效合成羟吲哚和吡咯并吲哚

N-芳基丙烯酰胺与氨基酸衍生物的α-氨基烷基化是通过银催化以中等至高收率实现的。该反应为合成官能化的吲哚提供了有效的策略，适用于各种价格便宜且易于获得的N-芳基丙烯酰胺和氨基酸。通过一锅中的脱保护和环化作用，可以轻松地将获得的羟吲哚转化为高密度官能化的吡咯并吲哚啉。