The aryl C-glycoside structure is, among the plenty of biologically active natural products, one of the distinct motifs embedded. Because of the potential bioactivity as well as the synthetic challenges, these structures have attracted considerable interest, and extensive research toward the total synthesis has been performed. This Review focuses on the synthetic strategies and tactics employed in the total synthesis of this class of natural products. The Introduction describes the historical background, structural features, and synthetic problems associated with aryl C-glycoside natural products. Next the Review summarizes the methods for constructing the aryl C-glycoside bonds. Completed total syntheses—and, in some cases, selected examples of incomplete syntheses—of natural aryl C-glycosides are also summarized. Finally described are the strategies for constructing polycyclic structures, which were utilized in the total syntheses.

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芳基C-糖苷天然产物的全合成：策略和策略

在许多具有生物活性的天然产物中，芳基C-糖苷结构是嵌入的独特基序之一。由于潜在的生物活性以及合成挑战，这些结构引起了相当大的兴趣，并且已经对全合成进行了广泛的研究。这篇综述着重于这类天然产物的全合成过程中所采用的合成策略和策略。引言描述了与芳基C-糖苷天然产物有关的历史背景，结构特征和合成问题。接下来的综述总结了构建芳基C的方法-糖苷键。还概述了天然芳基C-糖苷的完成的总合成（在某些情况下还包括不完全合成的某些示例）。最后描述了构建多环结构的策略，该策略已用于总合成中。