Keeping in mind the advantages of material-based systems over simple molecule-based systems, we have designed and developed three inorganic-organic hybrid systems by anchoring 1,8-naphthalimide derivatives to mesoporous silica nanoparticles for detection of free radicals. Prior to photophysical study, systems are characterized by spectroscopic, microscopic and thermo-gravimetric techniques. Steady state and time-resolved fluorescence studies demonstrate that the hydrazine based system is senstive towards detection of various free radicals. Cellular imaging study reveals cell permeability and toxicity study demonstrates the non-toxic nature of the material. These studies have suggested that present system has the potential to be used in various biological applications.

牢记基于材料的系统相对于基于简单分子的系统的优势，我们通过将1,8-萘二甲酰亚胺衍生物固定在介孔二氧化硅纳米粒子上以检测自由基，设计并开发了三种无机-有机杂化系统。在进行光物理研究之前，通过光谱，显微和热重技术对系统进行表征。稳态和时间分辨荧光研究表明，基于肼的系统对检测各种自由基非常敏感。细胞成像研究揭示了细胞的通透性，而毒性研究表明了该材料的无毒性质。这些研究表明，本系统具有在各种生物学应用中使用的潜力。