The main aim of this study was to characterize the diversity of extended-spectrum beta-lactamases (ESBLs) in Escherichia coli isolates from European free tailed-bats (Tadarida teniotis) in Portugal. ESBL-producing E. coli isolates were recovered from 14 of 146 faecal samples (9.6%) and a total of 19 isolates were completely characterized. The more prevalent beta-lactamase genes detected were blaCTX-M-1 (57.9%) and blaCTX-M-3 (36.8%), followed by blaSHV (31.6%), blaTEM (21.1%), blaOXA (10.5%) and blaCTX-M-9 (10.5%). Among other associated resistance genes studied, tet(A) and tet(B) were predominant and fimA was the main virulence factor detected. Phylogroups D (47.4%) and A (31.6%) were the more prevalent, followed by group B2 (21.1%). Bats are reservoirs of antimicrobial-resistant bacteria and resistance determinants and is important in further studies to identify the main sources of pollution in the environment, such as water or insects that may contain these multiresistant organisms.

中文翻译：

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关于从葡萄牙的欧洲无尾蝙蝠（Tadarida teniotis）生产大范围β-内酰胺酶（ESBL）大肠杆菌的第一份报告：一种隐藏污染问题的单一健康方法。

这项研究的主要目的是表征从葡萄牙的欧洲无尾蝠（Tadarida teniotis）分离出的大肠杆菌中的广谱β-内酰胺酶（ESBLs）的多样性。从146份粪便样本中的14份（9.6％）中回收了产生ESBL的大肠杆菌，并对其进行了完全鉴定。检测到的更普遍的β-内酰胺酶基因是blaCTX-M-1（57.9％）和blaCTX-M-3（36.8％），其次是blaSHV（31.6％），blaTEM（21.1％），blaOXA（10.5％）和blaCTX -M-9（10.5％）。在研究的其他相关抗性基因中，tet（A）和tet（B）占优势，fimA是检测到的主要毒力因子。毛病群D（47.4％）和A（31.6％）更为普遍，其次是B2组（21.1％）。