The renin‐angiotensin system (RAS) is a major contributor to the development of insulin resistance and its related complications. Egg white ovotransferrin‐derived tripeptides, IRW (Ile‐Arg‐Trp), IQW (Ile‐Gln‐Trp), or LKP (Leu‐Lys‐Pro) are previously identified as the inhibitors of angiotensin‐converting enzyme (ACE), a key enzyme in the RAS. This study aims at determining whether these peptides are effective in improving insulin resistance, and their mechanisms of action, in a rat derived skeletal muscle cell line (L6 cells).

中文翻译：

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卵清卵转铁蛋白衍生的ACE抑制肽改善了骨骼肌细胞中血管紧张素II刺激的胰岛素抵抗。

肾素-血管紧张素系统（RAS）是胰岛素抵抗及其相关并发症发展的主要因素。卵白卵转铁蛋白衍生的三肽，IRW（Ile-Arg-Trp），IQW（Ile-Gln-Trp）或LKP（Leu-Lys-Pro）先前被确定为血管紧张素转化酶（ACE）的抑制剂RAS中的关键酶。这项研究旨在确定这些肽在大鼠衍生的骨骼肌细胞系（L6细胞）中是否有效改善胰岛素抵抗及其作用机制。