After activation by chloride abstraction utilizing NaBArF as an activator (BArF = tetrakis(3,5-bis(trifluoromethyl)phenyl)borate), a complex of the general formula [RuCl₂(PHOX)₂] was utilized as a catalyst in propargylic substitution reactions, where PHOX is a phosphinooxazoline ligand. Oxygen and nitrogen-centered nucleophiles could be employed in the substitution of a propargylic acetate to obtain the corresponding propargylic substitution products in 87% to 9% isolated yields (45 °C, 16 h reaction time, toluene solvent, 1–2 mol% catalyst loading, 1–2 mol% activator).

中文翻译：

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通式[RuCl ₂（PHOX）₂ ]的钌配合物在炔丙基取代反应中作为前催化剂

使用NaBArF作为活化剂（BArF =四（3,5-双（三氟甲基）苯基）硼酸酯）通过氯化物提取进行活化后，将通式[RuCl ₂（PHOX）₂ ]的配合物用作炔丙基取代反应中的催化剂反应，其中PHOX是膦恶唑啉配体。氧和氮中心亲核试剂可用于乙酸丙炔酯的取代，以87％至9％的分离产率获得相应的丙炔取代产物（45°C，16 h反应时间，甲苯溶剂，1-2 mol％催化剂负载，1-2 mol％的活化剂）。