Solvent‐free extrusion emulsification (SFEE) is new technique for a twin‐screw extruder to prepare submicron‐sized particles (100–500 nm) without using hazardous solvents. The particle size is reliant upon the thickness of striated lamellae, which can be monitored rheologically based on the viscosity change occurring at the SFEE process. The lamellae coarsening rate is predominantly affected by the interfacial energy of the system when a surfactant is added but shows stronger dependency on viscosity change when interfacial growth between the polymer and water phases is solely determined by the end‐groups conversion into carboxylate species. For this latter case, the dissolution of the sodium hydroxide species and the kinetics of end‐groups conversion prove to be rate‐limiting phenomena to generating thinner striated lamellae. Additionally, the ionic strength of the system is notably important to the viscosity response and particle size produced, particularly when surfactant is not added. © 2018 American Institute of Chemical Engineers AIChE J, 64: 2113–2123, 2018

中文翻译：

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双螺杆挤出机内无溶剂的聚合物乳化

无溶剂挤出乳化（SFEE）是双螺杆挤出机无需使用危险溶剂即可制备亚微米级颗粒（100-500 nm）的新技术。粒度取决于条纹状薄片的厚度，可以根据SFEE工艺中发生的粘度变化，通过流变学方法进行监测。当添加表面活性剂时，薄片的粗化速率主要受体系界面能的影响，但当聚合物和水相之间的界面增长仅取决于端基转化为羧酸盐种类时，则显示出对粘度变化的依赖性更大。对于后一种情况，氢氧化钠物质的溶解和端基转化的动力学被证明是产生较薄条纹状薄片的限速现象。此外，该系统的离子强度对于粘度响应和产生的粒度特别重要，特别是在不添加表面活性剂的情况下。©2018美国化学工程师学会AIChE J，64：2113-2123，2018年