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Efficient Synthesis of Arylated Furans by a Sequential Rh‐Catalyzed Arylation and Cycloisomerization of Cyclopropenes
Angewandte Chemie International Edition ( IF 16.6 ) Pub Date : 2018-01-16 , DOI: 10.1002/anie.201712019
Xiaoming Wang 1 , Andreas Lerchen 1 , Constantin G. Daniliuc 1 , Frank Glorius 1
Affiliation  

A novel and efficient strategy for the synthesis of arylated furans was successfully developed by a RhIII‐catalyzed coupling of N‐phenoxyacetamides and cyclopropenyl esters. Mechanistic investigation reveals that the arylated furans are formed via arylation of the cyclopropenyl esters followed by cycloisomerization.

中文翻译:

通过顺序Rh催化的芳基化和环丙烯的环异构化有效合成芳基化的呋喃

通过Rh III催化的N-苯氧基乙酰胺和环丙烯基酯的偶联,成功开发了一种新的有效的芳基化呋喃合成策略。机理研究表明,芳基化的呋喃是通过环丙烯基酯的芳基化,然后进行环异构化而形成的。
更新日期:2018-01-16
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