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A nickel-catalyzed anti-carbometallative cyclization of alkyne–azides with organoboronic acids: synthesis of 2,3-diarylquinolines
Chemical Communications ( IF 4.9 ) Pub Date : 2017-12-22 00:00:00 , DOI: 10.1039/c7cc08408k
Gadi Ranjith Kumar 1, 2, 3, 4, 5 , Ravi Kumar 1, 2, 3, 4, 5 , Manda Rajesh 1, 2, 3, 4 , Maddi Sridhar Reddy 1, 2, 3, 4, 5
Affiliation  

An anti-carbonickelative cyclization via reversible alkenylnickel E/Z isomerization of 2-azido phenyl propargyl alcohols with aryl boronic acids is achieved using Ni(acac)2 as the catalyst to access 2,3-diaryl quinolines. It represents a rare example of trapping the vinyl metal intermediate with a nitrogen center, a non-carbon center electrophile.

中文翻译:

镍催化的炔基叠氮化物与有机硼酸的碳金属环化:2,3-二芳基喹啉的合成

一种-carbonickelative环化经由可逆alkenylnickel ë / Ž 2-叠氮基的异构化苯基炔丙基醇与芳基硼酸取得了使用酸为Ni(ACAC)2作为催化剂,以访问2,3-二芳喹啉。它代表了一个罕见的例子,即用氮中心(非碳中心的亲电试剂)捕获乙烯基金属中间体。
更新日期:2018-01-18
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