Sciadonic acid (Scia; 20:3Δ5,11,14) is a distinctive fatty acid (FA) with a polymethylene‐interrupted double bond at C5. It is specifically found in seeds from gymnosperms such as pine nuts. Published papers describe a decrease in liver and plasma triacylglycerols in rats fed with this nutriment. The present study seeks to identify the action mechanism of Scia on triacylglycerol synthesis. In this way, its nutritional effect on FA metabolism involving the Stearoyl‐CoA Desaturase 1 (SCD1) is investigated.

中文翻译：

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坐骨酸的降甘油三酸酯作用是通过抑制Δ9-去饱和酶的表达和活性来介导的

坐骨神经痛酸（Scia; 20：3Δ5,11,14）是一种独特的脂肪酸（FA），在C5处有一个多亚甲基中断的双键。它特别存在于裸子植物如松子的种子中。发表的论文描述了用这种营养喂养的大鼠肝脏和血浆三酰甘油的减少。本研究试图确定Scia对三酰基甘油合成的作用机理。通过这种方式，研究了其对涉及硬脂酰辅酶A去饱和酶1（SCD1）的FA代谢的营养作用。