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Cytosensing of cancer cells using antibody-based molecular imprinting: A short-review
Trends in Analytical Chemistry ( IF 13.1 ) Pub Date : 2017-12-21 , DOI: 10.1016/j.trac.2017.12.010
Mohammad Hasanzadeh , Nasrin Shadjou , Miguel de la Guardia

Rapid and effective differentiation between normal and cancer cells is an important objective for the diagnosis, prognosis and theranosis of tumours. This short review highlights some of the most recent developments on the application of molecular bioimprinting in detection of cancer cells using antibody-based cancer cell recognition method. The particular emphasis of this review is on sample-to-answer devices and approaches that enable down-stream investigation of the properties of the cells. Given the speed, portability, sensitivity and selectivity achieved using molecular bioimprinting technology on cancer cell monitoring, these methods hold the promise of transformative change in clinical practice.



中文翻译:

使用基于抗体的分子印迹技术对癌细胞进行细胞传感:简短回顾

正常细胞与癌细胞之间的快速有效分化是诊断,预后和肿瘤治疗的重要目标。这篇简短的评论重点介绍了分子生物印迹技术在使用基于抗体的癌细胞识别方法检测癌细胞中的最新进展。这项审查的特别重点是从样本到答案的设备和方法,这些设备和方法可以进行细胞特性的下游研究。考虑到使用分子生物印迹技术在癌细胞监测中实现的速度,便携性,敏感性和选择性,这些方法有望在临床实践中带来变革性的改变。

更新日期:2017-12-22
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