In this research, a facile strategy to obtain graphene isolated uniform Ag array membrane that are stable for long‐term use as surface enhanced Raman scattering (SERS) substrates is demonstrated. The fabrication process consisted of three main steps: interfacial assembly of Ag nanoparticles (NPs) into an array, transferring the Ag array to a membrane, and tightly wrapping the Ag array with graphene. The fabricated Ag array and graphene layer structure is tightly packed with effective electromagnetic coupling and electron transferring as confirmed by X‐ray photoelectron spectroscopy, UV‐vis spectra and Raman analysis. Owing to the uniform and effective electromagnetic coupling between Ag NPs and chemical enhancement from tightly wrapped graphene, this hierarchical membrane exhibited excellent SERS enhancing ability (an enhancement factor of 7.3 × 10⁸) and large area uniformity (with relative standard deviation less than 5.91% for 50 times of detection over an area up to 9 cm²). Due to the protection effect by graphene as both an isolation layer and an electron shuttle, this substrate showed out‐standing long‐term stability (stable more than 25 weeks). Specific functions of graphene in fluorescence quenching and photo‐bleaching inhibition further contributed to intrinsic Raman information access. The obtained flexible membrane based multi‐layer architecture is also easy of use for real application.

中文翻译：

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大面积均匀且长期稳定的石墨烯隔离纳米银阵列膜的表面辅助拉曼散射膜的过滤辅助制备。

在这项研究中，展示了一种简便的策略来获得石墨烯分离的均匀Ag阵列膜，该膜可长期稳定用作表面增强拉曼散射（SERS）衬底。制造过程包括三个主要步骤：将Ag纳米颗粒（NPs）界面组装成阵列，将Ag阵列转移到膜上，以及用石墨烯紧密包裹Ag阵列。X射线光电子能谱，UV可见光谱和拉曼分析证实了所制造的Ag阵列和石墨烯层结构紧密结合，具有有效的电磁耦合和电子转移能力。由于Ag NP之间均匀有效的电磁耦合以及紧密包裹的石墨烯的化学增强作用，这种分层膜具有出色的SERS增强能力（增强因子7.3×10⁸）和大面积均匀性（在9 cm ²的面积上进行50次检测时，相对标准偏差小于5.91％）。由于石墨烯既可作为隔离层又可作为电子穿梭物的保护作用，因此该基板表现出出色的长期稳定性（稳定超过25周）。石墨烯在荧光猝灭和光漂白抑制中的特定功能进一步促进了固有的拉曼信息访问。所获得的基于柔性膜的多层体系结构也易于在实际应用中使用。