Diabetic foot ulcers are serious and challenging wounds associated with high risk of infection and lower-limb amputation. Ulcers are deemed neuroischaemic if peripheral neuropathy and peripheral artery disease are both present. No satisfactory treatment for neuroischaemic ulcers currently exists, and no evidence supports one particular dressing. We aimed to assess the effect of a sucrose octasulfate dressing versus a control dressing on wound closure in patients with neuroischaemic diabetic foot ulcers.

中文翻译：

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患有神经缺血性糖尿病足溃疡患者的蔗糖八硫酸盐敷料与对照敷料（Explorer）：一项国际，多中心，双盲，随机，对照试验。

糖尿病足溃疡是严重且具有挑战性的伤口，与高感染风险和下肢截肢相关。如果周围神经病变和周围动脉疾病同时存在，则认为溃疡是神经缺血性的。目前尚无令人满意的神经缺血性溃疡治疗方法，也没有证据支持一种特殊的敷料。我们旨在评估蔗糖八硫酸盐敷料与对照敷料在神经缺血性糖尿病足溃疡患者伤口闭合中的作用。