A facile and direct intramolecular oxidative C(aryl)-H amidation reaction was developed for the synthesis of quinolino[3,4-b]quinoxalin-6(5H)-ones in moderate to excellent yields starting from readily available materials by tethering the adjacent N-methoxyamide and aryl portions in the presence of phenyliodine(III) bis(trifluoroacetate) at room temperature. This metal-free approach is a valuable addition to the traditional methods already available for the preparation of these molecules.

中文翻译：

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PIFA促进的分子内氧化C（芳基）-H酰胺化反应：喹啉[3,4- b ]喹喔啉-6（5 H）-ones的合成

从易得的材料上通过束缚分子间的连接，开发了一种简便且直接的分子内氧化C（芳基）-H酰胺化反应用于合成中等到极好产率的喹啉代[3,4- b ] quinoxalin-6（5 H）-酮。在室温下，在苯基碘（III）双（三氟乙酸酯）存在下，使相邻的N-甲氧基酰胺和芳基部分相邻。这种无金属方法是对这些分子制备中已经可用的传统方法的宝贵补充。