Horner syndrome results from an interruption of the oculosympathetic pathway. Patients with Horner syndrome present with a slightly droopy upper lid and a smaller pupil on the affected side; less commonly, there is a deficiency of sweating over the brow or face on the affected side. This condition does not usually cause vision problems or other significant symptoms, but is important as a warning sign that the oculosympathetic pathway has been interrupted, potentially with serious and even life-threatening processes. The oculosympathetic pathway has a long and circuitous course, beginning in the brain and traveling down the spinal cord to exit in the chest, then up the neck and into the orbit. Therefore, this syndrome with unimpressive clinical findings and insignificant symptoms may be a sign of serious pathology in the head, chest, or neck. This clinical review discusses how to identify the signs, confirm the diagnosis, and evaluate the many causes of Horner syndrome.

中文翻译：

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霍纳氏综合症：临床评价

霍纳综合征是由于眼球交感神经通路的中断而引起的。霍纳综合症患者的上眼睑略有下垂，患侧瞳孔较小；较不常见的是，患侧的额头或脸部出汗少。这种情况通常不会引起视力问题或其他明显症状，但是作为警告信号，表明眼交感神经通路已被中断，可能会导致严重甚至危及生命的过程，因此很重要。眼睑交感神经通路具有漫长而circuit回的过程，从大脑开始，沿着脊髓向下运动，到达胸部，然后沿着颈部进入眼眶。因此，这种临床表现不佳且症状不明显的综合征可能是头部，胸部或颈部严重病理的征兆。