Endogenous hydrogen sulfide (H₂S) has been acknowledged as the third important gasotransmitter and plays a vital role to human health and diseases. A "turn-on" near-infrared fluorescent probe DCM-PBA based on nucleophilic substitution–cyclization has been developed for the detection of hydrogen sulfide. The probe showed high selectivity and sensitivity toward H₂S and was successfully applied to imaging H₂S in HeLa cells.

中文翻译：

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基于亲核取代-环化的近红外荧光探针，用于硫化氢和生物成像的选择性检测

内源性硫化氢（H ₂ S）被认为是第三种重要的气体传输剂，对人类健康和疾病起着至关重要的作用。已经开发了一种基于亲核取代-环化的“开启”近红外荧光探针DCM-PBA，用于检测硫化氢。该探针显示出对H ₂ S的高选择性和敏感性，并成功应用于HeLa细胞中H ₂ S的成像。