A series of ketonitrones derived from isatin and indanone (INs) were synthesized and evaluated for their antiproliferative activities against several human cancer cell lines. Then, the antioxidant properties of these substrates were measured by the DPPH test to report their biological activity in terms of their spin trapping action. In particular, one substrate has showed very high biological and scavenging activity, probably due to the strong correlation between its spin trapping activity and structure.

中文翻译：

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新型靛红/茚满基硝酮 (INs) 作为自由基中间体的潜在自旋捕获剂的抗增殖活性†

合成了一系列源自靛红和茚满酮 (IN) 的酮硝酮，并评估了它们对几种人类癌细胞系的抗增殖活性。然后，通过 DPPH 测试测量这些底物的抗氧化性能，以报告它们在自旋捕获作用方面的生物活性。特别是，一种底物显示出非常高的生物和清除活性，这可能是由于其自旋捕获活性和结构之间的强相关性。