Abstract In this work halloysite (Hal) nanotubes were used as nanocontainers for salycilic acid (SA) in a perspective of its use in active packaging for food industry. The system Hal/SA was investigated for its ability to stabilize Hal suspensions by turbidimetry, its release kinetics in water by UV spectroscopy and its antibacterial activity against Pseudomonas fluorescens IMA 19/5 by Isothermal Micro Calorimetry (IMC). IMC is a sensitive and non-destructive technique and allows the study of a wide range of relatively slow processes (hours and days) in solutions. The system Hal/SA resulted to stabilize Hal suspension in water and to release SA in a controlled way over 50 h. Moreover the SA released by Hal/SA showed an antibacterial activity at lower concentrations than free SA, likely due to the close contact of bacteria and Hal in the reaction vessel.

中文翻译：

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埃洛石纳米管负载水杨酸的释放动力学和抗菌活性

摘要 在这项工作中，埃洛石 (Hal) 纳米管被用作水杨酸 (SA) 的纳米容器，因为它用于食品工业的活性包装。研究了 Hal/SA 系统通过浊度法稳定 Hal 悬浮液的能力、通过紫外光谱法在水中的释放动力学以及通过等温微量热法 (IMC) 对荧光假单胞菌 IMA 19/5 的抗菌活性。IMC 是一种灵敏且无损的技术，可用于研究溶液中各种相对缓慢的过程（数小时和数天）。Hal/SA 系统使 Hal 在水中的悬浮液稳定，并在 50 小时内以受控方式释放 SA。此外，Hal/SA 释放的 SA 在低于游离 SA 的浓度下显示出抗菌活性，