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Competitive annealing mediated isothermal amplification of nucleic acids†
Analyst ( IF 4.2 ) Pub Date : 2017-12-19 00:00:00 , DOI: 10.1039/c7an01569k
Rui Mao 1, 2, 3, 4, 5 , Lifei Qi 1, 2, 3, 4, 5 , Jianjun Li 1, 2, 3, 4, 5 , Ming Sun 6, 7, 8 , Zhuo Wang 1, 2, 3, 4, 5 , Yuguang Du 1, 2, 3, 4, 5
Affiliation  

A novel nucleic acid isothermal amplification method with high specificity, efficiency and rapidity was developed. The principle of primer design was achieved by slight modification of PCR primers. Acceleration probes were also explored. The newly developed method is of great potential for point of care diagnostics.

中文翻译:

竞争性退火介导的核酸等温扩增

开发了一种具有高特异性,高效率和快速性的新型核酸等温扩增方法。引物设计的原理是通过略微修饰PCR引物来实现的。还研究了加速度探头。新开发的方法在即时诊断方面具有巨大潜力。
更新日期:2017-12-19
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