An efficient one-pot approach to the synthesis of α,α-difluoroketone hydrazones has been developed via visible-light photoredox catalysis. The organic dye acts as an inexpensive and non-toxic photocatalyst, and could be recycled in 95% yield in a large-scale synthesis. This reaction occurs under mild conditions with high step-economy, a broad substrate scope, and excellent functional group compatibility. Moreover, the protocol is applicable to the late-stage functionalization of natural products.

中文翻译：

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可见光促进的有机染料催化的醛，肼和溴代二氟试剂三组分偶联†

通过可见光光氧化还原催化，已经开发出一种有效的一锅法合成α，α-二氟酮。有机染料充当廉价且无毒的光催化剂，可以大规模合成以95％的产率回收。该反应在温和的条件下进行，步骤经济性高，底物范围广，官能团相容性好。而且，该协议适用于天然产物的后期功能化。