In regard to tremendous toxicological effects of aflatoxin B1 (AFB1) and its major metabolite aflatoxin M1 (AFM1) on human health, quality assessment of food is of great importance. On the other hand, due to extremely low levels of these toxic metabolites in food and feed, the need to develop reliable and sensitive method is inevitable. Although, very different analytical techniques have been introduced for detection of them, hindrances such as time-consuming, labor-intensive, and highly-priced instruments have limited their uses. Aptasensors, as emerging methods, have opened new horizons for sensitive and selective detection of toxins. Aptamers are a new class of characteristic bio-recognition elements, provided by an in vitro process named SELEX (Systematic Evolution of Ligands by EXponential enrichments). This review discusses Aptasensors developed for detection of AFB1 and AFM1. Additionally, we aimed to investigate the advantages and disadvantages of these systems and introduce the best ones.

关于黄曲霉毒素B1（AFB1）及其主要代谢产物黄曲霉毒素M1（AFM1）对人体健康的巨大毒理作用，食品质量评估非常重要。另一方面，由于食品和饲料中这些有毒代谢物的含量极低，因此不可避免地需要开发可靠而灵敏的方法。尽管已经引入了非常不同的分析技术来检测它们，但是诸如耗时，劳动密集型和价格昂贵的仪器之类的障碍限制了它们的使用。适应性传感器作为新兴方法，为灵敏和选择性检测毒素开辟了新领域。适体是一类新型的特征性生物识别元件，由称为SELEX（通过指数富集的配体的系统进化）的体外过程提供。这篇评论讨论了为检测AFB1和AFM1而开发的Aptasensors。此外，我们旨在研究这些系统的优缺点，并介绍最佳系统。