We investigated the deposition pattern of microparticles with different particle diameters, shape factors, and initial flow conditions in a realistic human upper respiratory tract model. We identified a close relationship between the deposition fraction and the particle shape factor. The deposition fraction of the particles decreased sharply with increasing particle shape factor because of the decreasing drag force. We also found that the deposition varied at different positions in the upper respiratory tract. At low shape factors, the highest fraction of particles deposited at the mouth and pharynx. However, with increasing shape factor, the deposition fraction in the trachea and lungs increased. Moreover, for a given shape factor, larger particles deposited at the mouth and pharynx, which indicates that the deposition fraction of microparticles in the human upper respiratory tract is affected first and foremost by particle inertia as well as by the drag force.

我们在现实的人类上呼吸道模型中研究了具有不同粒径，形状因子和初始流动条件的微粒的沉积模式。我们确定了沉积分数与颗粒形状因子之间的密切关系。颗粒的沉积分数随着颗粒形状因子的增加而急剧下降，这是因为阻力减小了。我们还发现沉积物在上呼吸道的不同位置变化。在低形状因数下，最大部分的颗粒沉积在口腔和咽部。然而，随着形状因子的增加，气管和肺中的沉积分数增加。而且，对于给定的形状因子，较大的颗粒会沉积在口腔和咽部，