Nosocomial pneumonia is commonly associated with antimicrobial-resistant Gram-negative pathogens. We aimed to assess the efficacy and safety of ceftazidime-avibactam in patients with nosocomial pneumonia, including ventilator-associated pneumonia, compared with meropenem in a multinational, phase 3, double-blind, non-inferiority trial (REPROVE).

中文翻译：

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头孢他啶-avibactam与美罗培南在医院内肺炎，包括呼吸机相关性肺炎（REPROVE）中：一项随机，双盲，3期非劣效性试验。

医院内肺炎通常与耐药性革兰氏阴性病原体有关。我们旨在评估头孢他啶-avibactam与美罗培南在多国，三期，双盲，非自卑性临床试验中相比，对美罗培南在医院内肺炎（包括呼吸机相关性肺炎）患者中的疗效和安全性。