Electrospun nanofiber matrices are widely used as scaffolds for the regeneration of different tissues due to similarities with fibrous components of the extracellular matrix. These scaffolds could act as a substrate for inducing mechanical stimuli to cells. The main mechanical stimuli factor in nanofiber scaffolds for determining the cell behaviors is stiffness of single nanofibers. This paper especially highlights the finding that the young's modulus of single nanofibers can be obtained from aligned nanofibers matrix. It is assume that, the modulus of single nanofibers are equal to modulus of completely aligned nanofibers. However, due to difficulty of producing completely aligned nanofibers, the obtained modulus of single nanofiber wouldn’t have significant value. Therefore, we propose a new mathematical model to predict the stiffness of single nanofibers from non-perfectly aligned nanofibers matrix.

由于与细胞外基质的纤维成分相似，电纺纳米纤维基质被广泛用作不同组织再生的支架。这些支架可以作为诱导细胞机械刺激的底物。用于确定细胞行为的纳米纤维支架中的主要机械刺激因素是单根纳米纤维的刚度。本文特别强调发现可以从排列的纳米纤维基质获得单纳米纤维的杨氏模量的发现。假设单个纳米纤维的模量等于完全排列的纳米纤维的模量。然而，由于难以生产出完全取向的纳米纤维，所获得的单根纳米纤维的模量不会具有显着的价值。所以，