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DNA Synthesis by Primer Exchange Reaction Cascades
ChemBioChem ( IF 3.2 ) Pub Date : 2018-01-24 , DOI: 10.1002/cbic.201700639
Marcel Hollenstein 1
Affiliation  

Swap and extend: The autonomous synthesis of single‐stranded DNA molecules of arbitrary size and sequence composition can easily be achieved by primer exchange reaction (PER) cascades, in which the sequential polymerase‐mediated extension of DNA primers is guided by catalytic hairpins. This highlight illustrates the potential of this method for applications in DNA nanotechnology.
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中文翻译:

通过引物交换反应级联法合成DNA

交换和延伸:通过引物交换反应(PER)级联可以轻松实现任意大小和序列组成的单链DNA分子的自主合成,在该级联中,连续的聚合酶介导的DNA引物延伸由催化发夹引导。这一亮点说明了该方法在DNA纳米技术中的应用潜力。
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更新日期:2018-01-24
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