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Silent Cerebral Small-Vessel Disease Is Twice as Prevalent in Middle-Aged Individuals With Well-Controlled, Combination Antiretroviral Therapy–Treated Human Immunodeficiency Virus (HIV) Than in HIV-Uninfected Individuals
Clinical Infectious Diseases ( IF 11.8 ) Pub Date : 2017-12-13 , DOI: 10.1093/cid/cix1075 Antoine Moulignier 1 , Julien Savatovsky 2 , Lambert Assoumou 3 , François-Xavier Lescure 4 , Cédric Lamirel 5 , Ophelia Godin 3 , Nadia Valin 6 , Roland Tubiana 3, 7 , Ana Canestri 8 , Pascal Roux 2 , Jean-Claude Sadik 2 , Laurence Salomon 9 , Marie Abrivard 9 , Christine Katlama 3, 7 , Yazdan Yazdanpanah 4 , Gilles Pialoux 8 , Pierre-Marie Girard 3, 6 , Dominique Costagliola 3 , A Moulignier , A Moulignier , C Amiel , L Assoumou , A Canestri , I Cochereau , J Capeau , D Costagliola , O Godin , P M Girard , C Katlama , C Lamirel , F X Lescure , L Marchand , M Mazighi , M Obadia , M Paques , G Pialoux , E Plaisier , R Tubiana , N Valin , Y Yazdanpanah , P Yeni , A Moulignier , M Abrivard , A S Alonso , I Cochereau , P Koskas , C Lamirel , L Lopes , M Mazighi , M Obadia , P Roux , J C Sadik , L Salomon , J Savatovsky , V Vasseur , F X Lescure , M Chansombat , R Landman , B Phung , D Rahli , Y Yazdanpanah , P Yeni , C Katlama , L Lenclume , R Tubiana , M Valantin , P M Girard , J L Meynard , M Sebire , N Valin , G Pialoux , A Adda Liévin , C Amiel , J P Bastard , A Canestri , J Capeau , S Fellahi , M G Lebrette , E Plaisier , P Thibaut , M Paques , D Costagliola , L Assoumou , G Dos Santos , O Godin , L Marchand , P Girard , J P Vincensini ,
Clinical Infectious Diseases ( IF 11.8 ) Pub Date : 2017-12-13 , DOI: 10.1093/cid/cix1075 Antoine Moulignier 1 , Julien Savatovsky 2 , Lambert Assoumou 3 , François-Xavier Lescure 4 , Cédric Lamirel 5 , Ophelia Godin 3 , Nadia Valin 6 , Roland Tubiana 3, 7 , Ana Canestri 8 , Pascal Roux 2 , Jean-Claude Sadik 2 , Laurence Salomon 9 , Marie Abrivard 9 , Christine Katlama 3, 7 , Yazdan Yazdanpanah 4 , Gilles Pialoux 8 , Pierre-Marie Girard 3, 6 , Dominique Costagliola 3 , A Moulignier , A Moulignier , C Amiel , L Assoumou , A Canestri , I Cochereau , J Capeau , D Costagliola , O Godin , P M Girard , C Katlama , C Lamirel , F X Lescure , L Marchand , M Mazighi , M Obadia , M Paques , G Pialoux , E Plaisier , R Tubiana , N Valin , Y Yazdanpanah , P Yeni , A Moulignier , M Abrivard , A S Alonso , I Cochereau , P Koskas , C Lamirel , L Lopes , M Mazighi , M Obadia , P Roux , J C Sadik , L Salomon , J Savatovsky , V Vasseur , F X Lescure , M Chansombat , R Landman , B Phung , D Rahli , Y Yazdanpanah , P Yeni , C Katlama , L Lenclume , R Tubiana , M Valantin , P M Girard , J L Meynard , M Sebire , N Valin , G Pialoux , A Adda Liévin , C Amiel , J P Bastard , A Canestri , J Capeau , S Fellahi , M G Lebrette , E Plaisier , P Thibaut , M Paques , D Costagliola , L Assoumou , G Dos Santos , O Godin , L Marchand , P Girard , J P Vincensini ,
Affiliation
Silent cerebral small-vessel disease (CSVD) is defined as white matter hyperintensities, silent brain infarction, or microbleeds. CSVD is responsible for future vascular events, cognitive impairment, frailty, and shorter survival. CSVD prevalence among middle-aged people living with well-controlled human immunodeficiency virus (HIV) infection (PLHIV) is unknown.
中文翻译：
在控制良好，联合抗逆转录病毒疗法治疗的人类免疫缺陷病毒（HIV）的中年个体中，无症状的小脑血管疾病的发病率是未感染HIV的个体的两倍
静默性脑小血管疾病（CSVD）定义为白质高信号，静默性脑梗塞或微出血。CSVD负责未来的血管事件，认知障碍，虚弱和较短的生存期。尚不清楚控制良好的人类免疫缺陷病毒（HIV）感染（PLHIV）的中年人的CSVD患病率。
更新日期：2017-12-13
中文翻译：
在控制良好，联合抗逆转录病毒疗法治疗的人类免疫缺陷病毒（HIV）的中年个体中，无症状的小脑血管疾病的发病率是未感染HIV的个体的两倍
静默性脑小血管疾病（CSVD）定义为白质高信号，静默性脑梗塞或微出血。CSVD负责未来的血管事件，认知障碍，虚弱和较短的生存期。尚不清楚控制良好的人类免疫缺陷病毒（HIV）感染（PLHIV）的中年人的CSVD患病率。
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