当前位置: X-MOL 学术BDJ Open › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Actinic cheilitis: proposition and reproducibility of a clinical criterion
BDJ Open Pub Date : 2017-08-04 , DOI: 10.1038/bdjopen.2017.16
Nádia Antunes Poitevin 1 , Mariana Sudati Rodrigues 1 , Karen Loureiro Weigert 2 , Carmen Lúcia Rodrigues Macedo 3 , Rubem Beraldo Dos Santos 3
Affiliation  

Objectives/Aims:

The actinic cheilitis (AC) is a precancerous lip lesion seen as a consequence of chronic sun exposure. Clinically, the border between the lip’s skin and the semimucosa could be blurred; in the more aggressive cases, leucoplakia and ulcers also represent its clinical feature. It seems that no clinical criterion is universally accepted for this disease yet. Therefore, this study was carried out to make a proposition of a clinical score to actinic cheilitis (Grade I starting from dryness of vermilion to endured ulcers representing Grade IV) and to assess its reproducibility.

Materials and Methods:

Fifty subjects were assessed, most of whom were male, Caucasian farmers, with an average age of 46.12 (18–74) years. The obtained data were analysed by means of descriptive statistics and by Kappa test to assess the inter-examiners and the clinical Golden-Pattern concordance (95% CI).

Results:

During calibration, 15 patients were examined three times a week by each examiner (4) until Kappa test observed k=0.8 or more. In the main experiment, the inter-examiner concordance was classified between good (k=0.779; P<0.05) and very good (k=0.925; P<0.05) from the 35 examined subjects. With the Golden-Pattern, it was considered very good (k=0.812; P<0.05 to k=0.925; P<0.05).

Discussion:

Four examiners with different experiences could strongly suggest that after adequate calibration, it could be well applied by examiners with as much experience as a dental student.

Conclusions:

The authors concluded that the proposed classification was easily applied and had a very good reproducibility.



中文翻译:

光化性唇炎:临床标准的提议和可重复性

目标/目的:

光化性唇炎 (AC) 是一种癌前唇病变,被视为慢性日晒的结果。临床上,唇部皮肤和半黏膜之间的边界可能会模糊;在更具侵袭性的情况下,白斑和溃疡也代表其临床特征。似乎还没有普遍接受这种疾病的临床标准。因此,本研究旨在提出光化性唇炎的临床评分(从朱红色干燥到代表 IV 级的持久性溃疡的 I 级)并评估其可重复性。

材料和方法:

评估了 50 名受试者,其中大多数是男性高加索农民,平均年龄为 46.12(18-74)岁。通过描述性统计和 Kappa 检验对获得的数据进行分析,以评估检查者间和临床黄金模式一致性 (95% CI)。

结果:

在校准期间,每位检查者 (4) 每周检查 3 次 15 名患者,直到 Kappa 测试观察到k = 0.8 或更多。在主要实验中,来自 35 名被检查对象的考官间一致性分为良好(k = 0.779;P <0.05)和非常好(k = 0.925;P <0.05)之间。使用黄金模式,它被认为非常好(k =0.812;P <0.05 到k =0.925;P <0.05)。

讨论:

四位经验不同的检查员强烈建议,经过充分校准后,具有与牙科学生一样丰富经验的检查员可以很好地应用它。

结论:

作者得出的结论是,所提出的分类很容易应用,并且具有很好的可重复性。

更新日期:2017-08-04
down
wechat
bug