We describe a copper(I) catalyzed ortho‐chlorination of aromatic compounds via direct C−H activation by using hypervalent iodine reagent 1‐chloro‐1,2‐benziodoxol‐3‐one. This reaction showed high regioselectivity for the monochlorination of the C−H bonds of 2‐phenyl pyridines and was compatible for a wide range of nitrogen‐containing aromatics. Furthermore, the synthesized iodine(III) reagent was highly stable, recyclable, and can be employed in large‐scale syntheses of halo‐heteroarenes.

中文翻译：

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用高价碘（III）试剂1-1-氯1,2-苯并恶唑-3-酮对芳基CH键进行区域选择性氯化

我们描述了铜（I）通过使用高价碘试剂1-氯-1,2-苯并恶唑3-3-1通过直接的C-H活化来催化芳香族化合物的邻氯氯化。该反应对2-苯基吡啶的CH键的单氯化具有很高的区域选择性，并且与多种含氮芳族化合物相容。此外，合成的碘（III）试剂具有很高的稳定性，可回收性，可用于卤代-杂芳烃的大规模合成。