Current models theorizing on what the mitochondrial permeability transition (mPT) pore is made of, implicate the c-subunit rings of ATP synthase complex. However, two very recent studies, one on atomistic simulations and in the other disrupting all genes coding for the c subunit disproved those models. As a consequence of this, the structural elements of the pore remain unknown. The purpose of the present short-review is to (i) briefly review the latest findings, (ii) serve as an index for more comprehensive reviews regarding mPT specifics, (iii) reiterate on the potential pitfalls while investigating mPT in conjunction to bioenergetics, and most importantly (iv) suggest to those in search of mPT pore identity, to also look elsewhere.

当前关于线粒体通透性转变（mPT）孔组成的理论模型，暗示了ATP合酶复合物的c亚基环。但是，两项非常近期的研究，一项是关于原子模拟的研究，另一项是破坏所有编码c亚基的基因的研究，反驳了那些模型。结果，孔的结构元件仍然是未知的。本篇简短评论的目的是（i）简要回顾最新发现，（ii）用作对mPT细节进行更全面评论的索引，（iii）在与生物能学结合研究mPT时重申潜在的陷阱，最重要的是（iv）建议那些寻求mPT孔同一性的人也去别处寻找。