A set of five metal–organic frameworks, namely, [Cd₂(L)₂BIP(H₂O)₂·6H₂O]_n (1), [Ce(L)_1.5(H₂O)₂·H₂O]_n (2),[Sm(L)_1.5(H₂O)₂·3H₂O]_n (3),[Gd(L)_1.5(H₂O)₂·3H₂O]_n (4),[Ho(L)_1.5(H₂O)₂·3H₂O]_n (5), have been prepared under hydrothermal conditions (1,4-H₂L=1,4-Pheny lenedioxydiacetic acid; 1,4-BIP = 1,4-bis(2-pyridylmethyl)piperazi-ne; C2H5OH = EtOH). The long BIP ligand (N ⋯ N separation of ca. 8.355 Å) induces interpenetration of 1 to increase both the framework stability and the density of effective catalytic metal centers. Characterization of all complexes has been carried out by means of IR spectroscopy, single crystal and powdered sample X-ray diffraction (PXRD) through conventional and synchrotron radiation, Thermogravimetric (TG), fluorescent measurement (liquid and solid), DNA molecular docking, cancer cell apoptosis morphology through fluorescent inverted microscope, IC₅₀, which the cytotoxic activity of the complexes was tested against two different cancer and one normal cell lines. The results indicate that all the complexes are potential fluorescent light-emitting materials and the flour (2, 3, 4, 5) complexes present remarkable anti-cancer effect.

一组五个金属有机骨架，即[Cd ₂（L）₂ BIP（H ₂ O）₂ ·6H ₂ O] _n （1），[Ce（L）_1.5（H ₂ O）₂ ·H ₂ O] _n （2），[Sm（L）_1.5（H ₂ O）₂ ·3H ₂ O] _n （3），[Gd（L）_1.5（H ₂ O）₂ ·3H ₂ O] _n （4），[Ho（L）_1.5（H ₂ O）₂ ·3H ₂ O] _n （5），是在水热条件下制备的（1,4-H ₂ L = 1,4-苯二酸二烯二乙酸； 1,4-BIP = 1,4-bis （2-吡啶基甲基）哌嗪烯； C 2 H 5 OH ＝ EtOH）。长的BIP配体（N⋯N分离，约8.355Å）引起1的互穿以增加骨架的稳定性和有效催化金属中心的密度。已经通过红外光谱，通过常规和同步辐射的单晶和粉末样品X射线衍射（PXRD），热重（TG），荧光测量（液体和固体），DNA分子对接，癌症对所有复合物进行了表征通过荧光倒置显微镜IC ₅₀观察细胞凋亡的形态，测试了该复合物对两种不同的癌症和一种正常细胞系的细胞毒活性。结果表明，所有的复合物是潜在的荧光发光材料和面粉（2，3，4，5）复合物具有显着的抗癌作用。