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A Practical Three-Step Synthesis of Vinylferrocene
Synthesis ( IF 2.6 ) Pub Date : 2017-12-11 , DOI: 10.1055/s-0036-1589142
Radovan Šebesta , Kristína Plevová , Brigita Mudráková

Abstract

An improved, short and efficient synthesis of vinylferrocene is reported. This three-step synthesis includes Friedel–Crafts acylation, reduction, and a one-pot mesylation/elimination step to afford the target compound in 62% yield over three steps.

An improved, short and efficient synthesis of vinylferrocene is reported. This three-step synthesis includes Friedel–Crafts acylation, reduction, and a one-pot mesylation/elimination step to afford the target compound in 62% yield over three steps.



中文翻译:

实用的三步法合成乙烯基二茂铁

摘要

报道了一种改进的,短而有效的乙烯基二茂铁的合成。此三步合成包括Friedel-Crafts酰化,还原和一锅甲磺酸化/消除步骤,在三个步骤中以62%的产率提供目标化合物。

报道了一种改进的,短而有效的乙烯基二茂铁的合成。此三步合成包括Friedel-Crafts酰化,还原和一锅甲磺酸化/消除步骤,在三个步骤中以62%的产率提供目标化合物。

更新日期:2017-12-11
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