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Inflammation, ROS, and Mutagenesis.
Cancer Cell ( IF 50.3 ) Pub Date : 2017-Dec-11 , DOI: 10.1016/j.ccell.2017.11.015
Asmaa El-Kenawi , Brian Ruffell

It has long been hypothesized that reactive oxygen species (ROS) are responsible for the association between chronic inflammatory diseases and increased tumor incidence. In this issue of Cancer Cell, Canli et al. now demonstrate that amplified ROS production specifically by myeloid cells is sufficient to promote intestinal mutagenesis.

中文翻译:

炎症,ROS和诱变。

长期以来,人们一直认为活性氧(ROS)是造成慢性炎症性疾病和增加肿瘤发生率的原因。在本期《癌细胞》中,Canli等人。现在证明,髓细胞特有的扩增的ROS产生足以促进肠道诱变。
更新日期:2017-12-11
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